Regorafenib

Regorafenib 40 mg (Stivarga) is an anticancer drug that is approved to treat cancer of the rectum and colon that has spread (metastatic cancer). It is given to patients who have already been treated with other cancer medications but failed to recover. This medicine averts tumor progress. It is also used for the treatment of rare tumors that affect the stomach, intestines, and esophagus.

What Is It And How It Works?

Stivarga is a targeted cancer medication. It comes in the form of a 40 mg tablet available at Heal Pharmacy website. This product belongs to the kinase inhibitors that work by hindering the activity of an abnormal protein that prevents cancer cells from replicating. This medicine prevents cancer cells from making new blood vessels which they necessitate to grow. It slows down or stops the spread of cancer cells to other body parts.

Regorafenib uses include:

Colon and rectal cancer (Colorectal cancer)

It begins in the large intestine or rectum and spreads to other body parts but fails to improve while using certain other medicines such as Oxaliplatin, Irinotecan, and Fluoropyrimidine-based therapy or anti-EGFR therapy.

Gastrointestinal stromal tumors (GIST)

This type of tumor progresses in the stomach esophagus or intestine. This medicine is prescribed to patients with metastatic, locally advanced, or unresectable GIST who do not get the desired effects of certain other anti-cancer drugs such as Sunitinib.

Hepatocellular carcinoma (HCC)

It is a type of liver cancer. This medication is prescribed to patients who have already been treated with Nexafar.

How to Use This Medicine Correctly

It is accessible as an oral tablet that should be taken by mouth. Usually, healthcare professionals advise taking it after a low-fat meal. A typical Regorafenib dose is once a day for 3 weeks and then skip the medication for 1 week. This is the 4-week cycle of this drug. Your doctor may prescribe to repeat the cycle.

The particular dose may vary depending on the severity of your condition and how your body reacts to the treatment. For maximum benefits try to take this tablet every day at the same time. Carefully track your doctor’s instructions and take this medicine correctly as prescribed.

Regorafenib 40 mg

Swallow the whole tablet with water. Do not try to chew, crush, or split the tablet. If you are unable to swallow the tablets talk to your doctor for the right advice. Take it after a low-fat or low-calorie meal as suggested by your healthcare provider. For instance, 1 portion of cereal (30g), a glass of skimmed milk, and a glass of apple juice.

Whether you take this medicine with or without a meal can impact the amount of medicine that gets into your bloodstream. Your doctor may modify the dose or ask you to discontinue taking this medicine during the treatment. Take this medicine for the prescribed period even if your condition improves.

Regorafenib colon cancer medication may shrivel the cancer or stop its growth for a period. Generally, it is recommended to take this medicine as long it benefits you without causing serious side effects. Make sure you regularly go for blood pressure checkups and liver function tests.

If You Missed A Dose

If you forgot to take a dose, take it as soon as you can. If you realize that you missed a dose when it is almost time for your next dose, forget the missed one and take your next scheduled dose. You should not take double doses to compensate for the missed dose.

If You Get Too Much Of The Medicine

Taking too much of this drug can cause symptoms of overdose and it can be dangerous. Overdose symptoms that can get serious are trouble breathing, seizures, and collapsing. Call your healthcare professional or the nearest poison control center for a medical emergency.

The Most Important Things You Should Know While Using This Medicine

• • Store this medicine safely at room temperature protecting it from heat and moisture.
  • Leave the tablets in their original packaging until you have to take them. Do not put these
  • tablets into your daily pill box.
  • Once you open the bottle use the tablets within 7 weeks and carefully discard the remaining tablets.
  • This medication is prescribed to you so you should not share it with anyone else even if their symptoms seem similar.
  • The safety and effectiveness of this medicine in kids is not recognized. Regarding the use of this drug in children, consult your pediatrician. Special care may be required during pediatric use.
  • Discuss with your healthcare provider if you consume alcohol or use illegal drugs. These products may increase the risk of possible adverse effects.
  • To avoid skipping doses make sure you get your medicine refill from Heal Pharmacy before you are out of medicine.

Warnings

Before using Stivarga and during the treatment your doctor needs to determine the advantages and possible risks considering certain factors.

Allergic Reaction:

Inform your healthcare professional if you have or ever had an allergic reaction or unusual reaction to Stivarga, any other drugs, or other products.

Health Problems and Medications:

Inform your healthcare team if you have or ever had liver disease, high blood pressure, heart disease, a bleeding disorder, or any other serious health condition. Your healthcare provider should be aware of any prescription or over-the-counter medicines, health supplements, herbal products, or vitamins you are taking.

Surgery:

If you have to undergo any surgical treatment, inform your surgeon that you are using Stivarga tablets. This medicine may interfere with wound healing. Your healthcare provider will ask you to discontinue this medicine 2 weeks before surgery. Cautiously follow the instructions given by your healthcare team concerning the use of this medicine.

Pregnancy:

Usually, this medicine is prescribed to men however whether you are a male or female, use effective birth control methods to avoid pregnancy during the treatment. You need to avoid getting pregnant for at least 2 months after you stop this medicine. This drug may harm the unborn baby if any of the parents use it during baby planning.

Liver Problems:

This medicine can cause serious liver issues. Seek your doctor’s attention if you have vomiting, nausea, sleep troubles, jaundice, or dark urine while using this medicine.

Where to Buy

Cancer medications are prescribed for the long term which means you have to use them regularly. That means you have to spend huge on Regorafenib cost. You may not be able to get this medicine from retail pharmacies. So the most convenient way to get this medicine is to buy it from Heal Pharmacy online.

At Heal Pharmacy you can purchase generic and brand-name medicines of various doses and forms. Generic medicines are available at low prices at Heal Pharmacy as compared to brand-name medicines. Heal Pharmacy is offering quality medicines at affordable prices. You can avail of free shipping, discount coupons, and great savings on your medicine purchase only at the Heal Pharmacy website.

Regorafenib Side Effects

Just like any cancer medication, Regorafenib colon cancer drug may also cause side effects. These symptoms include:

• • Weakness
  • Diarrhea
  • Tiredness
  • Loss of appetite

Usually, these symptoms go away within a few days. In case your symptoms last longer or become worse call your health care provider.

Drug Interactions

Stivarga may interact with certain other medications. Combining two medicines may interfere with how they work and also increase the risk of possible side effects.

Medicines you should avoid while taking Sitvarga include:

• • Warfarin
  • Voriconazole
  • Telithromycin
  • John’s Wort
  • Phenytoin
  • Phenobarbital
  • Ketoconazole
  • Itraconazole
  • Irinotecan
  • Carbamazepine
  • Ibuprofen

There may be other medicines that can interact with Stivarga tablets. Make sure you talk to your healthcare provider about the possible drug instructions and how you can use these medicines safely.

Other Interactions:

Grapefruit may raise the level of this medicine inside the body. Avoid eating grapefruit, drinking grapefruit juice, or consuming grapefruit-containing products while taking Stivarga.

Conclusion

Stivarga tablets are used for the treatment of metastatic colon and rectum cancer, liver cancer, and gastrointestinal stromal tumors. This drug impedes the progression of tumors by targeting the cancer cell proteins. Generally, this medicine is used to treat certain types of cancer in patients who have already been treated with other cancer medications that did not go well.

Frequently Asked Questions

What kind of medicine is Stivarga?

This drug is known as a cancer growth blocker. It specifically targets signals that are necessary for the growth of cancer cells and prevents their progression.

How long I can take this medicine safely?

Stivarga treatment includes a 4-week cycle. For 3 weeks you have to take this medicine daily and then you have to skip it for the 4^th week. The cycle can be repeated considering the severity of the condition and the occurrence of side effects.

How much does it cost?

The exact Regorafenib price depends on certain factors such as the pharmacy you choose to get your medicine and the country you live in. At Heal Pharmacy you can buy this medicine at reasonable rates. The average price of this drug is around $24151 for 84 tablets. If you can’t spend on expensive brand-name medication, you can get generic medicine from Heal Pharmacy. For additional savings, Heal Pharmacy presents great offers to its customers.

What is the shelf life of Stivarga tablets?

As per the manufacturer, the shelf life of Stivarga is 7 weeks after you open the original bottle. Contact your healthcare professional if you have any queries.